Creates the Holistic Overdose Prevention and Equity Act. Creates the Harm Reduction Program Board, with certain requirements. Provides that the Department of Public Health shall issue grants to harm reduction providers, with certain requirements. Establishes a Chief Harm Reduction Officer within the Department. Provides for a place-based approach to harm reduction pilot program. Provides for local government training and continuing education. Provides that naloxone shall be made readily available to all staff and individuals in prisons and jails, with certain requirements. Provides for medication for opioid use disorder and fentanyl testing. Restricts the use of abstinence-only or sobriety requirements to housing, with certain requirements. Limits home rule powers. Makes findings. Defines terms. Amends the Department of Professional Regulation Law of the Civil Administrative Code of Illinois, the Counties Code, the County Jail Act, the Unified Code of Corrections, the Hospital Licensing Act, and the Overdose Prevention and Harm Reduction Act to make conforming changes.

Amends the Mental Health and Developmental Disabilities Administrative Act. Provides that, beginning January 1, 2026, providers of adult day services for individuals with developmental disabilities shall receive an add-on payment of $1 for transportation, per trip, for any distance beyond 15 miles from the adult day service program location. Effective January 1, 2026.

Appropriates $4,000,000 from the General Revenue Fund to the Department of Human Services for a grant to Chicago Survivors for family and community services. Effective immediately.

Amends the Probation Community Service Act. Provides that the court may give credit toward the fulfillment of community service hours for participation in activities and treatment as determined by court services.

Creates the Consumer Product Return Act. Provides that a retail mercantile establishment shall not limit the method of return or refund to the issuance of store credit when accepting the return of an unopened or unused consumer product from a consumer. Provides that a retail mercantile establishment may require a consumer to provide reasonable proof of purchase and may use any reasonable method to verify that the consumer purchased the unused or unopened consumer product before processing a return, refund, or exchange. Sets forth limitations and exceptions to the Act. Provides that a violation of the Act is a business offense with a fine not to exceed $25. Provides that a retail mercantile establishment shall not be fined in excess of $500 in a calendar year for violations of the Act. Allows a person to bring an action for injunctive relief to obtain compliance with the Act. Limits home rule. Effective July 1, 2027.

Provides that the Act may be referred to as the Responsible Gun Manufacturing Act. Amends the Criminal Code of 2012. Provides that a person commits the offense of unlawful possession of weapons when the person knowingly manufactures, sells, or offers to sell, purchases, receives, manufactures, imports, or transfers a convertible pistol. Establishes penalties. Provides exemptions. Provides that a machine gun also includes any convertible pistol equipped with a switch. Defines "convertible pistol", "switch", and "common household tool". Amends the Consumer Fraud and Deceptive Business Practices Act. Provides that reasonable controls by firearm industry members include reasonable procedures, safeguards, and business practices that are designed to prevent the installation and use of a switch with a firearm. Contains a severability provision.

Creates the Emergency Digital Communication Pilot Permits Act. Allows the Department of Transportation to issue pilot permits for digital public safety communication devices on State highway rights-of-way. Provides that digital public safety communication devices shall be operated solely by a unit of local government, shall not display commercial advertising, and must be installed on municipally owned infrastructure with emergency override functionality. Requires the Department to adopt rules to implement the Act. Effective immediately.

Appropriates $960,000 from the General Revenue Fund to the Department of Agriculture for costs associated with the Crop Insurance Rebate Initiative to provide incentives for at least 1,000,000 acres of eligible land. Effective July 1, 2025.

Amends Public Act 103-0589. Increases the Fiscal Year 2025 appropriation to the Department of Agriculture from the Partners for Conservation Fund for grants to Soil and Water Conservation Districts for ordinary and contingent administrative expenses from $4,500,000 to $8,500,000. Effective immediately.

Appropriates $1,500,000,000 from the General Revenue Fund to the Metropolitan Mobility Authority Additional Operating Funding Fund. Effective July 1, 2025.

Appropriates $300,000 from the General Revenue Fund to the Department of Public Health for grants to the Les Turner ALS Foundation for research on Amyotrophic Lateral Sclerosis (ALS). Effective July 1, 2025.

Amends the Interscholastic Athletic Organization Act. Provides that a public school or public postsecondary educational institution that offers, operates, or sponsors interscholastic or intercollegiate athletics shall provide equal athletic opportunities for members of both sexes. Provides that a school may operate or sponsor single-sex teams if the selection for such teams is based upon competitive skill or the activity involved is a contact sport. Provides that a school that participates in competitions or athletic events with or against other schools shall designate each team, competition, or athletic event as (i) for males, men, or boys; (ii) for females, women, or girls; or (iii) coeducational or mixed. Provides that a school or athletic association that is participating in a competition or an athletic event with or against another school that operates, sponsors, or permits athletic events or competitions may not allow any male to compete for, against, or with a team designated for females, women, or girls. Provides that a school or athletic association that operates, sponsors, or permits athletic events or competitions may not allow certain actions. Provides that a governmental entity, licensing or accrediting organization, athletic association, or school may not consider a complaint, open an investigation, or take adverse action against a school for complying with the amendatory provisions. Provides for private causes of action. Makes other changes.

Creates the Property Tax Levy Relief Act of 2026. Provides that the State Board of Elections shall cause a statewide advisory question of public policy concerning the levying of taxes on parcels of real property to be submitted to the voters at the general election to be held on November 3, 2026. Provides that the State Board of Elections shall immediately certify the question to be submitted to the voters of the entire State to each election authority in Illinois. Repeals the Act on January 1, 2027.

Amends the Chicago School District Article of the School Code. Provides that the Chicago Board of Education shall (rather than may), by majority vote, appoint a general superintendent of schools to serve pursuant to a performance-based contract for a term ending on June 30 of the third calendar year after the appointment. Provides that the general superintendent shall have all of the powers and duties of a chief executive officer as set forth in the Article. Effective immediately.

Creates the Definitions of Sex-Based Terms Act. Defines, for purposes of State statutes and administrative rules, the meaning of the following terms: "boy", "father", "female", "girl", "male", "man", "mother", "sex", and "woman".