US Federal 2025-2026 Regular Session

US Federal Senate Bill SB4440

Introduced
 
Introduced
4/29/26  

Caption

Clinical Trial Modernization Act

Summary

The Clinical Trial Modernization Act would create a set of federal incentives and legal safe harbors intended to increase participation in clinical trials, especially among underrepresented populations. It authorizes the Secretary of Health and Human Services to award grants and contracts for community education, outreach, recruitment, and investigator training, with an emphasis on community health centers, rural sites, tribal areas, multilingual materials, and partnerships with community-based organizations, including unions and frontline health care workers. The bill also amends federal fraud-and-abuse laws and tax law to make it easier for sponsors to reduce financial barriers to trial participation. It would clarify that certain participant reimbursements—such as travel, transportation, and meal expenses—do not violate the Civil Monetary Penalties Law or Anti-Kickback Statute if they are broadly available and designed to improve inclusion. It would also protect the free provision of necessary digital health technologies for trial participation, permit sponsors to pay patient cost-sharing obligations under specified safeguards, and exclude up to $2,000 per year of approved clinical trial remuneration from gross income.

Impact

The bill would affect the Social Security Act, the Anti-Kickback Statute, the Civil Monetary Penalties Law, the False Claims Act, and the Internal Revenue Code. In practical terms, it would create new federal protections for sponsor-funded participant support, including reimbursement of certain expenses, payment of cost-sharing, and provision of digital tools, while imposing conditions intended to prevent abuse and preserve existing Medicare and other federal coverage rules. It would also add a new income-tax exclusion for certain clinical trial payments, which could reduce tax burdens for participants and make enrollment more accessible.

Sentiment

The bill appears generally supportive of clinical research modernization and broader access to trials, with a clear emphasis on equity, rural access, and inclusion of populations historically underrepresented in research. The text reflects a pro-participation, pro-access approach rather than a restrictive one, and the bipartisan sponsorship suggests a constructive policy posture. No committee transcript or recorded vote information was provided, so there is no documented floor or committee sentiment beyond the bill’s structure and stated purpose.

Contention

The main policy tension is between expanding access and avoiding improper inducements or overuse of federal health care funds. The bill addresses this by requiring that participant support be broadly available, not tied to product purchase, capped or limited in certain ways, and subject to informed consent, written protocols, and independent oversight. Potential points of concern for critics could include the interaction with anti-kickback and false-claims rules, the possibility of sponsor payments influencing enrollment, and the administrative complexity of ensuring compliance with Medicare and other federal coverage requirements.

Companion Bills

US HB3521

Related Clinical Trial Modernization Act

Previously Filed As

US HB3521

Clinical Trial Modernization Act

US SB3564

NIH Clinical Trial Integrity Act

US HB6867

NIH Clinical Trial Integrity Act

US SB1230

Marijuana; clinical research trials

US SB778

Clinical Research Pharmacies and Clinical Trials - Permits and Ownership

US HB1426

Clinical Research Pharmacies and Clinical Trials - Permits and Ownership

US AJR117

Designates third full week of May of each year as "Clinical Trials Awareness Week" and May 20 of each year as "Clinical Trials Volunteers Appreciation Day" in NJ.

US HB2075

AN ACT to amend Tennessee Code Annotated, Title 9; Title 33; Title 53; Title 63 and Title 68, relative to clinical trials.

US SB2149

AN ACT to amend Tennessee Code Annotated, Title 9; Title 33; Title 53; Title 63 and Title 68, relative to clinical trials.

US HB1065

Cancer clinical trial program.

Similar Bills

No similar bills found.