Video & Transcript Research : 'mathematics methods'
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MN
Minnesota 2025-2026 Regular Session
House Higher Education Finance and Policy Committee 3/11/25
Higher Education Finance and Policy
US
US Federal 2025-2026 Regular Session
US House Floor Proceedings (Monday, April 7, 2025)
US Federal House Floor Meeting
Transcript Highlights:
- So, what is wrong with teaching about Charles Drew, an African-American who discovered the method by
- So, what is wrong with teaching about Charles Drew, an African-American who discovered the method by
- So, what is wrong with teaching about Charles Drew, an African-American who discovered the method by
- So, what is wrong with teaching about Charles Drew, an African-American who discovered the method by
- So, what is wrong with teaching about Charles Drew, an African-American who discovered the method by
NH
Transcript Highlights:
- the New Hampshire Department of Education are numbers I've used in my testimony and also simple mathematics
- 01:17:33.040>
and <01:17:33.280>also <01:17:33.679>simple <01:17:34.000>mathematics - my testimony and also simple mathematics my testimony and also simple mathematics will<01:17:35.040
NH
Transcript Highlights:
- that is recognized for providing a world-class education in science, technology, engineering, and mathematics
- :28.240>
and science, technology, engineering, and science, technology, engineering, and mathematics Our <05:59:30.638>career <05:59:31.040>and <05:59:31.680>technical mathematics- Our career and technical mathematics.
NH
New Hampshire 2025 Regular Session
House Education Funding (01/30/2025)
Transcript Highlights:
- Representative Maguire, yes, the sort of moving average—and I'm an engineer by training, so mathematics
- <04:09:51.159>
my <04:09:51.359>training <04:09:51.760>so <04:09:52.199>mathematics - <04:09:52.800>
is from my training so mathematics is from my training so mathematics is something
Summary:
The hearing focused on HB 563, which would revise the education funding formula for pupils receiving special education services by replacing the current single special education amount with three differentiated categories. Representative Rick Ladd, the prime sponsor, said the bill largely tracks a House-passed version from the prior session with minor figure adjustments, and explained that the proposal uses projected FY26 amounts for three categories based on time in general education versus more intensive placements. He also noted that the bill does not address catastrophic aid directly, but that special education aid, CAT aid, and proration all remain issues for later work sessions.
Ladd and supporters argued that weighted categories better reflect actual costs and are more sustainable than treating all IEPs the same. Representative Margaret Drye said the approach was one of the best ideas from the education funding subcommittee and urged the committee to support differentiated aid. Representative Ames asked how the category amounts were derived, and Ladd said Category A follows the FY26 base, Category B is a higher weight, and Category C is a still higher weight for more intensive services, though he acknowledged the exact multipliers were developed earlier and could be revisited. He also said the committee would continue discussing whether the weights are appropriate and how they interact with CAT aid.
Testimony from Bonnie Dunham strongly opposed the bill. She argued that funding based on placement rather than actual service need would create incentives to move students into more restrictive settings, could stigmatize children with labels such as "Category C," and would undermine the least restrictive environment requirements under federal special education law. She described her son’s experience in inclusive settings as beneficial and said the bill would have penalized the district for serving him there. In response to questions, she said schools and parents should base funding on the child’s actual needs and costs, not on placement, and urged the committee to recommend the bill inexpedient to legislate.
MN
Transcript Highlights:
- specific to the delivery method specific to the delivery method selection<00:10:36.320>
for - <00:15:59.240>
selection <00:15:59.560>of delivery method selection of delivery method - this is an Innovative uh delivery method this is an Innovative uh delivery method allowing<00:21
- how we use that that procurement method how we use that that procurement method uh<00:43:14.200>
- able to to utilize a different method able to to utilize a different method within<01:18:57.480>
OK
Transcript Highlights:
- That one method.
- approved methods.
- approved methods.
- approved methods.
- We heard this morning about Method 1621. This is a screening method only.
Summary:
The meeting focused on the use of biosolids on farm and ranch land, with testimony from Oklahoma State University experts, a conservation official, and an engineering representative about the benefits, risks, and regulatory implications. Dr. Lusk described OSU’s long history of soil fertility research and said biosolids can provide nutrients and organic matter, but also may carry contaminants such as PFAS, heavy metals, pharmaceuticals, microplastics, and pathogens. He emphasized that many questions remain unanswered, especially about contaminant uptake into soil, crops, livestock, and humans, and said existing EPA and Oklahoma DEQ regulations address some treatment and application standards but may not fully cover PFAS. Dr. Arnell expanded on nutrient management, explaining that biosolids can function similarly to manure as a fertilizer source, especially for nitrogen and phosphorus, but should be tested, incorporated into soil, and applied under permit conditions to reduce runoff and other losses. He said PFAS testing methods are not yet standardized and that more research is needed to determine sampling protocols, movement in soil, and long-term effects.
Committee members asked whether farmers and ranchers should be notified of risks, whether PFAS is currently tested, how many counties use biosolids, and what research would be needed for a dissertation-level study. The witnesses generally agreed that landowners should be informed of known risks and uncertainties, but said the science is still developing. Dr. Arnell said a unified testing method is needed before reliable PFAS monitoring can be done, and suggested that a multi-year study would be required to understand soil movement, crop uptake, and livestock impacts. Greg Scott of the Oklahoma Conservation Commission framed the issue as a waste-management problem, noting that human waste streams contain contaminants and that soil type affects how pollutants move; he said sandy soils pose greater movement risks than clay soils and that current best practice is incorporation, careful timing, and avoiding steep or sensitive sites. He also said PFAS are widespread and not naturally occurring in the way some other compounds are, and that liability and cleanup costs are major concerns.
Mary Elizabeth Mock of Garver Engineering focused on the practical and financial consequences of a possible moratorium on land application, saying most of Oklahoma’s biosolids are currently land applied and would otherwise have to go to landfills. She warned that many landfills are nearing capacity, tipping fees could rise sharply, and cities such as Tulsa and Norman could face large increases in disposal costs, which would ultimately be borne by ratepayers and taxpayers. She also said septic system maintenance costs could rise if land application options shrink, potentially leading to deferred maintenance and system failures. Mock urged a tiered, data-driven approach to PFAS regulation and said advanced treatment technologies may help in the future, but they are still emerging and expensive. No votes were taken; the session consisted of presentations and member questions.
LA
Louisiana 2026 Regular Session
Transportation, Highways and Public Works May 26th, 2026
Transportation, Highways & Public Works
Transcript Highlights:
- Florida tested multiple bidding award methods, including average bid price.
- The federal government does not recognize this contracting method.
- I think behind part of this concept, there... contracting method.
- This method is not used anywhere in America.
- The issues are coming up on page two on the average bid method. And so... ...its bid method.
Keywords:
highway maintenance, signage, transportation safety, DOTD, infrastructure, public safety, federal grants, job creation, Utility Terrain Vehicles, UTVs, safety regulations, transportation, Louisiana, task force, vehicle operation, legislation, accidents, HCR112, House Concurrent Resolution 112, Louisiana Highway 1
Summary:
The House Transportation Committee met on May 26 with a quorum present and took up several resolutions and one Senate bill. SCR 64 created a task force to study construction management at risk (CMAR) in Louisiana public works; an amendment added representatives from the Louisiana Associated General Contractors and Associated Builders and Contractors, and the resolution was reported with amendments. HR 282 created a task force to study utility terrain vehicles with state agencies; an amendment added the State Fire Marshal, and it was also reported with amendments.
The committee then considered SB 513 on public works project delivery methods. The bill originally included an average-bid award method for certain pilot projects, along with airport design-build provisions. Testimony from a Reason Foundation analyst and from the Louisiana Associated General Contractors raised concerns that average-bid contracting could encourage collusion, raise costs, and lacked supporting data or use by U.S. transportation departments, while airport design-build was supported. The committee adopted an amendment in concept to strike the average-bid provisions, leaving the airport-related design-build language in place, and SB 513 was reported with amendments by a vote of 11 yeas and 4 nays.
The committee also reported SCR 62 favorably, which urges DOTD to evaluate school zones on state highways in response to safety concerns and near misses, including a fatal incident referenced by the author. HCR 112 was reported favorably to study flooding on Louisiana Highway 1 in Shreveport, and HR 275 was reported favorably to study an interstate highway signage maintenance and reporting program. The meeting concluded after all items were disposed of and the committee adjourned.
NH
New Hampshire 2025 Regular Session
House Criminal Justice and Public Safety (02/12/2025)
Criminal Justice and Public Safety
Transcript Highlights:
- And we're also looking at all kinds of creative and alternative methods, and I really think about it
- And we're also looking at all kinds of creative and alternative methods, and I really think about it
- And we're also looking at all kinds of creative and alternative methods, and I really think about it
- And we're also looking at all kinds of creative and alternative methods, and I really think about it
- start getting at this speed, you start talking about a head-on collision, and you're getting into mathematics
WA
Washington 2025-2026 Regular Session
House Local Government Jun 11th, 2026
Transcript Highlights:
- If we're talking to... ...to moving forward with any of these methods.
- So in addition to these two ILA methods, there are ILA methods related to unincorporated islands, which
- And as you look at the election method, for instance, or I should say the petition method and some of
- That is one of the methods, the interlocal agreement methods, that was adopted, I believe, in 2020.
- Don't know what the best methods of enforcement are.
Summary:
The committee held a work session on local government issues, beginning with an update from the State Building Code Council on four legislatively mandated code amendments now in CR-102 rulemaking: temporary emergency shelters, reduced minimum dwelling unit size, multiplex housing up to three stories and six units, and single-exit apartment buildings up to six stories. Council staff also described a separate embodied-carbon appendix proposal that remains under public review, with testimony both supporting and opposing it. Members asked about the rationale for some of the code limits, including the restriction on connecting multiplex buildings.
The committee then heard a panel on annexations from MRSC, Pierce County, and the Association of Washington Cities. Witnesses reviewed annexation methods, including petition, election, and interlocal agreement approaches, and said larger annexations are increasingly using interlocal agreements because they can address infrastructure, revenue sharing, and public process concerns. They described barriers such as inconsistent local standards, the cost of infrastructure, referendum risk, census requirements, and the difficulty of persuading residents and local officials to support annexation. Members asked about the five-year restriction on residential zoning changes in one annexation method and whether a hearing examiner could reduce political pressure on local decision-makers.
A second panel discussed subdivision reform. The Master Builders Association urged raising the short-plat threshold within urban growth areas to 30 lots as a simpler first step, citing permitting delays and added housing costs. The City of Spokane described implementation problems with recent housing laws, including uncertainty about how to review plats under HB 1110, lot-splitting administration, and added notice requirements for unit lot subdivisions. AWC said there was broad agreement that subdivision decisions should be more administrative, but public hearings remained a point of disagreement. The committee also heard from FutureWise, the Washington State Association of Counties, and Lewis County on county development regulation and enforcement, with witnesses emphasizing underfunded code enforcement, inconsistent standards between counties and cities, and the need for better coordination, incentives, and possibly stronger enforcement tools. No votes were taken; the chair said the committee would continue working on possible solutions in future sessions.
LA
Louisiana 2026 Regular Session
Transportation, Highways and Public Works May 26th, 2026
Transcript Highlights:
- Florida tested multiple bidding award methods, including average bid price.
- The federal government does not recognize this contracting method.
- This method is not used anywhere in America.
- The issues are coming up on page two on the average bid method. And so... Its bid method.
- Okay, so the vote is to adopt the amendment set to strike the average bid method.
Summary:
The House Transportation Committee met on May 26 and considered several resolutions and one Senate bill dealing with transportation project delivery, vehicle safety, school-zone safety, flooding, and highway signage. The committee first took up SCR 64, which creates a task force to study construction management at risk (CMAR) for public works. An amendment added representatives from Louisiana Associated General Contractors and Associated Builders and Contractors to the task force, and the resolution was reported with amendments. The committee also heard HR 282, which creates a task force to study utility terrain vehicles with Louisiana State Police and other stakeholders; an amendment added the State Fire Marshal, and the resolution was reported with amendments.
The most extensive discussion centered on SB 513, which addressed public works project delivery methods and included a proposal for an average-bid award method as well as design-build authority for airports and vertiports. Testimony from a Reason Foundation policy analyst and a Louisiana Associated General Contractors representative opposed the average-bid concept, arguing it lacked U.S. precedent, could encourage collusion, and could raise costs, while airport-related design-build provisions were supported. The committee adopted an amendment in concept to remove the average-bid language, then reported SB 513 with amendments by a vote of 11 yeas and 4 nays.
The committee also reported SCR 62 favorably, which urges DOTD to evaluate all school zones on state highways in response to safety concerns and near misses involving crossing guards and distracted driving. In addition, HCR 112 was reported favorably to study flooding on Louisiana Highway 1 in Shreveport, and HR 275 was reported favorably to study an interstate highway signage maintenance and reporting program. The meeting concluded after all items were acted on and the committee adjourned.
WA
Washington 2025-2026 Regular Session
House Local Government Jun 11th, 2026 at 01:30 pm
Local Government
Transcript Highlights:
- So in addition to these two ILA methods, there are ILA methods related to sort of the unincorporated
- And as you look at the election method, for instance, or I should say the petition method and some of
- That is one of the methods, the interlocal agreement methods, that was adopted, I believe, in 2020. .
- ..methods that was adopted, I believe, in 2020.
- That method, though, does not determine what can be built.
VT
Transcript Highlights:
- <00:30:11.200>
of utilize speech as a method of utilize speech as a method of communication - <00:30:59.600>
of were unable to use this meth method of were unable to use this meth method - method of known as rapid prompting method of communication<00:31:46.080>
for <00:31:46.399> - method as namely the rapid prompting method as well<00:32:04.480>
as <00:32:04.799>facilitated - alternative methods of communication. alternative methods of communication.
Summary:
The House began with devotional remarks and then handled several procedural referrals. Senate bills 198 and 323 were referred to the Committee on Ways and Means under House Rule 35A because they affect state revenue, and Senate Bill 326 was also referred to Ways and Means after the Transportation Committee reported it favorably with amendment. House Resolution 18, supporting preservation of the Julian Scott birthplace in Johnson, was read by title and referred to the Committee on Corrections and Institutions under House Rule 52.
The chamber then read a series of adopted House concurrent resolutions honoring Vermont schools and individuals, including the Fair Haven Union High School Slater bowling team, the Hartford High School Hurricanes girls ice hockey team, the Hartford girls basketball team, Theres Black as Vermont Mother of the Year, and the Mount Mansfield Union High School girls tennis team. Members made brief announcements welcoming some of the honorees and guests to the chamber, including the Mount Mansfield tennis team, Theres Black, the Fair Haven bowling team, and others.
The main floor action was on House Resolution 17, affirming that all Vermonters are presumed competent to communicate and must be provided communication resources of their choice. The Human Services Committee chair explained the resolution grew out of testimony on alternative communication methods, including facilitated communication and rapid prompting method, and said the committee heard from people with lived experience, professionals, and written testimony from medical and speech-language organizations. The committee reported the resolution out 9-0-2, and the House adopted it. The House then took up Senate Bill 209, relating to prohibiting civil arrest in sensitive locations, and proceeded to its third reading and concurrence-with-amendment question.
KY
Kentucky 2025 Regular Session
House Standing Committee on Natural Resources & Energy (2-13-25)
Transcript Highlights:
- excluding low-cost monitoring methods often relied upon by local organizations.
- excluding low-cost monitoring methods often relied upon by local organizations.
- methods for emission testing or monitoring methods that's been approved by the EPA for compliance and
- applicable data collection method applicable data collection method methods<00:08:59.680>
for - testing or methods for Mission testing or monitoring<00:09:01.120>
methods <00:09:01.480>that's
Keywords:
Meeting Start 00:00
Attendance Roll Call 00:38
HB 137 Discussion 01:30
HB 137 Roll Call Vote 16:24
HB 196 Discussion 17:21
HB 196 Roll Call Vote 21:59, 958, all
Summary:
The Natural Resources and Energy Committee held its first meeting of the 2025 session, welcomed several new members, and confirmed a quorum. The committee first took up House Bill 137 on air quality monitoring. The sponsor and committee substitute were presented as requiring scientifically defensible, quality-assured data for air pollution enforcement, with the sponsor saying citizen complaints could still prompt agency inspections. A Kentucky Resources Council attorney testified in opposition, arguing the bill could limit low-cost community monitoring, conflict with the Clean Air Act’s credible evidence provisions, and undermine community efforts to identify pollution hotspots. After discussion, the committee adopted the substitute and passed HB 137 with favorable expression.
The committee then considered House Bill 196, dealing with mining emergency technicians. The sponsor said the bill responds to the decline in coal mining and smaller mine operations, and that it was developed with the Energy and Environment Cabinet and was not opposed by the Kentucky Coal Association or the UMWA. The bill would require one medic for mines with 10 or fewer miners, two for larger operations up to 50, and one additional medic for each additional 50 miners, with the sponsor saying the change would help small mines avoid shutting down shifts when a medic is unavailable. A question about the ratio above 50 was answered by noting the language came from the cabinet and was not being changed. The committee then passed HB 196 with favorable expression.
At the close of the meeting, the chair reminded members that the committee would continue using the 24-hour rule for amendments and committee substitutes and that agendas would generally be sent out the day before meetings.
LA
Louisiana 2026 Regular Session
House of Representatives May 27th, 2026
Louisiana House Floor Meeting
Transcript Highlights:
- I don't disagree, but I'm not sure that it substantiates that we're going after teachers that mathematically
Bills:
SCR59, SCR70, HR275, HR279, HR282, HR289, HR307, HCR112, SCR61, SCR62, SCR64, SB121, HR310, HR314, HR316, HR317, HR321, HCR117, SCR5, SCR29, SCR33, SCR37, SCR63, SCR30, SCR40, SCR65, HCR3, HCR49, HCR66, HCR67, HB54, HB137, HB321, HB368, HB386, HB414, HB431, HB552, HB555, HB578, HB590, HB593, HB618, HB638, HB670, HB692, HB707, HB708, HB715, HB718, HB732, HB741, HB748, HB776, HB796, HB807, HB822, HB848, HB856, HB887, HB888, HB917, HB921, HB1082, HB1243, HB1246, HB1, HB2, HB42, HB45, HB71, HB79, HB126, HB133, HB159, HB213, HB218, HB222, HB289, HB291, HB312, HB313, HB324, HB352, HB383, HB398, HB403, HB429, HB457, HB459, HB549, HB571, HB579, HB591, HB608, HB616, HB624, HB766, HB769, HB783, HB804, HB864, HB874, HB909, HB951, HB971, HB983, HB1005, HB1017, HB1051, HB1056, HB1126, HB1186, HB1193, HB1223, HB1224, HB1235, HB1249, SB259, SB295, SB312, SB348, SB444, SB485, SB441, SB149, HB359, SB29, SB43, SB78, HB463, HB998, SB197, SB268, SB123, SB276, SB326, SB80, HB901, HR20, HR74, HCR65, HCR71, HCR98, HB284, HB306, HB341, HB366, HB393, HB458, HB577, HB603, HB605, HB614, HB625, HB646, HB733, HB752, HB773, HB798, HB911, HB955, HB996, HB1035, HB1069, HB1113, HB1140, HB1180, HB1191, HB1240, HB1255, SB82, SB89, SB97, SB479, HB74, HB119, HB134, HB210, HB258, HB468, HB784, HB870, HB953, HB956, HB1117, HB1236, SB42, SB208, SB217, SB274, SB300, SB341, SB379, SB382, SB387, SB401, SB449, SB487
Keywords:
Major Richard Star Act, veterans, military retirement, disability compensation, VA benefits, combat-wounded, medically retired, military retirees, service members, veterans benefits, Department of Veterans Affairs, Department of Defense, concurrent receipt, retirement offset, combat-related disability, bipartisan support, memorial resolution, Congressional memorial, Louisiana delegation, Richard Star
KY
Kentucky 2025 Regular Session
Budget Review Subcommittee on Transportation (10-15-25)
Transcript Highlights:
- what I will do is I will ask our first presenters, who will be talking about alternative delivery methods
- related to alternative delivery methods related to alternative delivery methods about<00:04:35.759
- these alternative, you know, methods these alternative, you know, methods when<00:32:12.320>
- I'm just saying we're offering you if there's other methods that we can make... capabilities.
- As a topline feedback from our industry, we're supportive of alternative delivery methods.
Keywords:
00:05 Call to Order and Roll Call
01:20 Road Projects
46:30 Approval of Minutes
46:50 Railroads
57:26 Adjournment, 958, all
Summary:
The Budget Review Subcommittee on Transportation met without a quorum, so it could not approve the minutes. The chair announced an Eastern Kentucky University health forum later that day and then proceeded with testimony on alternative delivery methods for road projects. Jason Sawala of the Kentucky Transportation Cabinet and Chad Laroo of the Kentucky Association of Highway Contractors were sworn in and introduced themselves.
Sawala explained KYTC’s use of alternative delivery tools, including design-build, construction manager/general contractor (CMGC), and public-private partnerships (P3s). He said the cabinet’s goal is to deliver the best value to taxpayers in terms of quality, cost, and time, and emphasized that alternative delivery is most useful on projects with special circumstances such as innovation needs, specialized technology, complex constructibility, schedule pressure, or early contractor input. He cited the cabinet’s wrong-way driving prevention project as an example where design-build helped evaluate technologies and coordinate with stakeholders such as EMS and first responders.
He also outlined the main tradeoffs: alternative delivery can improve collaboration and sometimes accelerate schedules, but it also brings risks related to right-of-way acquisition, utility relocation, changing scope, and the need for dedicated staff and compressed decision-making. He stressed that these methods are not a cure-all and are not appropriate for every project, while noting that traditional design-bid-build remains effective for most of KYTC’s work.
Representative Branscum responded favorably, saying early contractor involvement is valuable and consistent with his experience in the vertical construction world. No votes or formal actions were taken because the committee lacked a quorum.
AR
Transcript Highlights:
- Let's go on to the method of finance. Thank you, Mr. Chair.
- The first two methods of finance are with U of A Jonesboro.
- Item C is an alternative delivery method project.
- Item C is an alternative delivery method project.
- or the traditional RFP method.
Summary:
The review subcommittee met to consider a supplemental agenda, methods of finance, an alternative delivery project, discretionary grants, and a large slate of construction, out-of-state, and in-state contracts. The supplemental item was a $2.6 million out-of-state contract with Tyler Technologies for a mobile app that would let citizens access state services through a single sign-on, initially for DFA vehicle and licensing services, with possible expansion to other agencies. Members also reviewed five methods of finance, including University of Arkansas projects for roof and cooling tower replacements, a new $100 million academic classroom building at U of A Fayetteville, a police department renovation at UA Fort Smith, and a boiler/chiller replacement at Hope-Texarkana. Questions focused on project timing, why some items were being reviewed after work had begun, and the high estimated cost of the Fayetteville classroom building; DFA explained that projects under $250,000 are not reviewed and that the larger project was still in design and would later seek a guaranteed maximum price.
The committee also reviewed two DHS discretionary grants: one for targeted youth advocacy in southwest Arkansas and another adding $582,000 for family-centered treatment training and implementation. In the services contract section, members discussed construction-related contracts, including an ASMSA electrical scope increase tied to three-phase power requirements and the U of A Fayetteville architect contract for the classroom building. Out-of-state contracts included major items such as ACT Education’s $17 million amendment to provide required pre-ACT testing for 9th and 10th graders, a $12.5 million DFA contract for rural health transformation grant management, DHS’s $16.5 million EBT services contract with updated chip-card and fraud-prevention features, and ADH’s special procurement for the Behavioral Risk Factor Surveillance System survey. The committee also reviewed U of A system consulting contracts for financial advisory and sponsorship strategy work, with university officials saying the outside expertise was needed for specialized planning and revenue-generation efforts.
In-state contracts covered corrections reentry services, nursing board investigations, foster care and child welfare services, DHS office janitorial work, emergency management radio system expansion, veterans’ home nursing staffing, and UAMS grants consulting. A lengthy exchange centered on the Department of Corrections’ reentry housing contract, with members pressing officials about vacant beds and urging fuller use of the program, while corrections staff said placements depend on screening and eligibility. Another discussion addressed the balance between out-of-state and in-state contracting, with a member noting the large dollar volume going to out-of-state vendors and asking whether Arkansas vendors receive any preference; State Procurement said current law does not allow an in-state preference. The committee approved the supplemental agenda, the methods of finance, the alternative delivery project, the discretionary grants, and the contract lists, and then received routine reports and an emergency action report before adjourning.
AZ
Transcript Highlights:
- So yeah, so here are some of the biomarker discovery methods used.
- I will go over some more methods to identify these biomarkers, but what's really important to know is
- that in my project I am not just using one method to identify a top biomarker, and the reason being
- . in all five or in all seven of these methods, whereas there were some that didn't appear at all.
- “How this works is it’s kind of like a lock-and-key method.
Summary:
The Committee on Science and Technology met to hear a presentation from Ananya Lakaraju, a Hamilton High School junior, on her research project using metabolomics and machine learning to identify potential salivary biomarkers for major depressive disorder. She described using a UCSD saliva metabolomics dataset, statistical methods such as Spearman correlation, Mann-Whitney U, and PLS-DA, and an ensemble AI model with SHAP and permutation importance to identify metabolites and pathways associated with depression. She said the work suggested several novel biomarkers, with some metabolites and pathways showing stronger associations with depression than others, and noted that her model achieved about 90% accuracy and a 97% AUC in distinguishing depressed from non-depressed samples.
Lakaraju also discussed a drug-discovery component of the project, using pathway analysis and molecular docking in UCSF Chimera to identify a target protein and potential compounds that might block a depression-related pathway. She said flupinazine showed the lowest binding energy in her simulations. Members asked questions about what the metabolites were, whether the findings were novel, how the saliva samples were obtained, and how the app she developed would be used. She explained that the data came from an online dataset rather than direct sample collection, that some top-ranked compounds were exogenous and not likely biomarkers, and that the app was intended to supplement AI results with mood and behavioral information because the model is not a doctor and could still be wrong.
The committee praised the presentation and discussed the broader implications for AI policy and mental health diagnostics. Lakaraju said she became interested in coding through robotics and later combined that interest with biology, and she emphasized her goal of making mental health assessment more objective and holistic. The meeting ended with members thanking her for the presentation and adjourning without any formal votes or legislative action.
US
US Federal 2025-2026 Regular Session
US House Floor Proceedings (Wednesday, March 4, 2026)
US Federal House Floor Meeting
Transcript Highlights:
- 42-year career as a civilian employee of the Navy, West learned to program computers and solve mathematical
- 42-year career as a civilian employee of the Navy, West learned to program computers and solve mathematical
- :17.839>
computers <00:42:18.720>and <00:42:19.119>solve <00:42:19.760>mathematical - program computers and solve mathematical program computers and solve mathematical problems<00:42
WY
Transcript Highlights:
- So obviously the 441 account and the 446 account as it is today are both healthy, but the mathematics
- So obviously the 441 account and the 446 account as it is today are both healthy, but the mathematics
- both healthy account as it is today are both healthy but<02:14:31.280>
the <02:14:31.520>mathematics it <02:14:32.719>is <02:14:33.599>57 <02:14:34.159>million but the mathematics- on it is 57 million but the mathematics on it is 57 million versus<02:14:35.040>
13 <02:14:35.360